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Vaccines Against Allergies / Rudolf Valenta ; Robert L. Coffman

PPN=1746469188; in Bibliotheksbestand, Treffer: 1

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MedienartE-Book [E-Book]
VerfasserValenta, Rudolf
Titel Vaccines Against Allergies / Rudolf Valenta ; Robert L. Coffman
PersonCoffman, Robert L.
VeröffentlichungBerlin, Heidelberg : Springer Berlin / Heidelberg, 2011
©2011
Umfang / Format 1 online resource (188 pages)
Anmerkungen Description based on publisher supplied metadata and other sources.
SpracheEnglisch
ISBN9783642200540
NummerEBL798764 (EBL)
ebr10844221 (EBR)
MIL336589 (MYL)
EBC798764 (EBC)
029180155 (EBP)
1746469188 (K10Plus-Nummer)
Schriftenreihe (Current Topics in Microbiology and Immunology Ser. ; v.352)
Schlagwörter Allergy desensitization..
Allergy
Electronic books
Inhalt Vaccines against Allergies celebrates the one hundred year anniversary of allergen-specific immunotherapy. Today allergen-specific immunotherapy is well established as the only allergen-specific and disease-modifying treatment for IgE-mediated allergies and has long-lasting effects.
Inhalt Intro -- Vaccines against Allergies -- Preface -- Contents -- Contributors -- 128 Immunological Approaches for Tolerance Induction in Allergy -- Abstract -- 1…Introduction -- 2…The Immune Response to Allergens is Regulated by T cells -- 3…Tolerance -- 4…Current Treatments for Allergy -- 5…Tolerance Induction -- 5.1 The T Cell Response and Cytokine Secretion -- 5.2 Histamine and Histamine Receptors in Tolerance Induction -- 5.3 B Cells in Tolerance Induction -- 5.4 Innate Immunity and Tolerance Induction -- 6…Improving Current Immunotherapy Strategies -- 6.1 Allergen: Immunogenicity and Allergenicity -- 6.2 Type of Allergen -- 6.2.1 Native Allergens -- 6.2.2 'Allergoid'xe ''Allergoids': Chemically Modified Allergens -- 6.2.3 Recombinant Allergens -- 6.3 Modality: Route of Dosing -- 6.4 Adjuvant -- 7…Future Perspectives -- 8…Conclusion -- References -- 129 Clinical Experience with Recombinant Molecules for Allergy Vaccination -- Abstract -- 1…Considerations for Optimal Allergen Specific Immunotherapy -- 2…Allergen Variants with Reduced IgE-Binding Activity -- 3…Recombinant Grass and Birch Pollen Allergens -- 4…Recombinant Hypoallergenic Variants of Birch Pollen Allergen Bet v 1 -- 5…Recombinant Cat Allergen Fel d 1 -- 6…Ragweed Amb a 1 -- 7…Where Do We Go from Here? -- References -- 125 Allergen-Specific Immunotherapy with Recombinant Allergens -- Abstract -- 1…Introduction -- 2…Strategies for Improving Efficacy of Allergen-Specific Immunotherapy -- 3…Clinical Trials -- 4…Clinical Efficacy and Side Effects of Recombinant Allergens -- 4.1 Recombinant Grass Allergen Immunotherapy -- 4.2 Recombinant Birch Allergen Immunotherapy -- 4.3 Recombinant Birch Allergen Derivatives Immunotherapy -- 5…Discussion -- 5.1 Clinical Efficacy and Safety of Recombinant Allergens -- 5.2 Clinical Efficacy and Safety of Recombinant Hypoallergenic Derivatives.

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